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Publications

                                                                            2021


Anh T.T.V., Mostafa A., Rao Z., Pace S., Schwaiger S., Kretzer C., Temml V., Giesel C., Jordan P.M., Bilancia R., Weinigel C., Rummler C., Waltenberger B., Hung T., Rossi A., Stuppner H., Werz O.*, Koeberle A.* (2021) From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharmaceutica Sin, in press. doi.org/10.1016/j.apsb.2021.04.011


Baunach M, Chowdhury S, Stallforth P, Dittmann E (2021) The Landscape of Recombination Events that Create Nonribosomal Peptide Diversity. Mol. Biol. Evol. doi:10.1093molbev/msab015/6108112


Cai C, Gu K, Zhao H, Steinhagen S, He P, Wichard T (2021) Screening and verification of extranuclear genetic markers in green tide algae from the Yellow Sea. PLoS ONE 16:e0250968


Carrasco Flores D, Fricke M, Wesp V, Desiro D, NKniewasser A, Hölzer M, Marz M, Mittag M (2021) A MARINE CHLAMYDOMONAS SP. EMERGING AS AN ALGAL MODEL. J Phycol 57:54-69.


Cooper RE, Wegner C-E, Küsel K (2021) Draft Genome Sequence of Pseudomonas sp. Strain FEN, Isolated from the Fe- and Organic Matter-Rich Schlöppnerbrunnen Fen. Microbiol. Res. Announc. 10: e01017-01020.


Dose B, Niehs SP, Schrelach K, Shahda S, Florez LV, Kaltenpoth M, Hertweck C (2021) Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts. ChemBioChem. doi:10.1002/cbic.202100089


Dose B, Thongkongkaew T, Zopf D, Kim HJ, Bratovanov EV, Garcia-Altares M, Scherlach K, Krabbe J, Ross C, Hermenau R, Niehs SP, Silge A, Hniopek J, Schmitt M, Popp J, Hertweck C (2021) Multimodal Molecular Imaging and Identification of Bacterial Toxins Causing Mushroom Soft Rot and Cavity Disease. ChemBioChem. doi:10.1002/cbic.202100330


Friedrich L, Cingolani G, Ko Y-H, Iaselli M, Miciaccia M, Perrone MG, Neukirch K, Bobinger V, Merk D, Hofstetter RK, Werz O, Koeberle A, Scilimati A, Schneider G (2021) Learning from nature: From a marine natural product to synthetic cyclooxygenase-1 inhibitors by automated de novo design. Adv. Sci., e2100832.


Gama S, Hermenau R, Frontauria M, Milea D, Sammartano S, Hertweck C, Plass H (2021) Iron Coordination Properties of Gramibactin as Model for the New Class of Diazeniumdiolate Based Siderophores. Chem Eur J 27:2724-2733. doi:10.1002/chem.202003842


Hotter V, Zopf D, Kim HJ, Silge A, Schmitt M, Aiyar P, Fleck J, Matthäus C, Hniopek J, Yan Q, Loper J, Sasso S, Hertweck C, Popp J, Mittag M (2021) A polyyne toxin produced by an antagonistic bacterium blinds and lyses a green microalga. bioRxiv: doi: https://doi.org/10.1101/2021.03.24.436739


Jagusch H, Werner M, Koenis D, Dalli J, Werz O, Pohnert G (2021) 14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae. ACS Pharmacol. Transl. Sci. 27:1188-1194.


Jordan PM, Andreas N, Groth M, Wegner P, Weber F, Jäger U, Küchler C, Werz O, Serfling E, Kamradt T, Dudeck A, Drube S. (2021) ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids. Immunology doi: 10.1111/imm.13386.


Lee SR, Guo H, Yu JS, Park M, Dahse HM, Jung WH, Beemelmanns C, Kim KH (2021) Revised structural assignment of azalomycins based on genomic and chemical analysis. Org. Chem. Front. DOI: 10.1039/d1qo00610j.


Li J, Halitschke R, Li D, Paetz C, Su H, Heiling S, Xu S, Baldwin IT (2021) Controlled hydroxylations of diterpenoids allow for plant chemical defense without autotoxicity. Science 371:255-260. doi:10.1126/science.abe4713


Li Q, Cooper RE, Wegner C-E, Taubert M, Jehmlich N, von Bergen M, Küsel K (2021) Insights into Autotrophic Activities and Carbon Flow in Iron-Rich Pelagic Aggregates (Iron Snow). Microorganisms 9, 1368.


Malabarba J, Meents AK, Reichelt M, Scholz SS, Peiter E, Rachowka J, Konopka-Postupolska D, Wilkins KA, Davies JM, Oelmüller R, Mithöfer A (2021) ANNEXIN1 mediates calcium-dependent systemic defense in Arabidopsis plants upon herbivory and wounding. New Phytol. 231: 243-254


Mohr J.F., Baldeweg F., Deicke M., Morales-Reyes C.F., Hoffmeister D., Wichard T. (2021) Frankobactin Metallophores Produced by Nitrogen-Fixing Frankia Actinobacteria Function in Toxic Metal Sequestration. J. Nat.Prod. 84: 1216-1225.


Molloy EM, Dell M, Haensch VG, Dunbar KL, Feldmann R, Oberheide A, Seyfarth L, Kumpfmüller J, Horch T, Arndt HD, Hertweck C (2021) Enzyme-Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia. Angew. Chem. Int. Ed. 60: 10670-10679.


Murry R, Traxler L, Pötschner J, Krüger T, Kniemeyer O, Krause K, Kothe E (2021) Inositol Signaling in the Basidiomycete Fungus Schizophyllum commune. J Fungi 7:470. doi:10.3390/jof7060470


Nahor O, Morales-Reyes CF, Califano G, Wichard T, Golberg A, Israel A (2021) Flow cytometric measurements as a proxy forsporulation intensity in the cultured macroalga Ulva (Chlorophyta). Bot Mar. doi:10.1515/bot-2020-0050


Nasufovic V, Küllmer F, Bößneck J, Dahse H, Görls H, Bellstedt P, Stallforth P, Arndt H (2021) Total Synthesis and Bioactivity Mapping of Geodiamolide H. Chem Eur J. doi:10.1002/chem.202100989


Oelmuller R (2021) Threat at One End of the Plant: What Travels to Inform the Other Parts? Int J Mol Sci 22 (6):29.


Pace S., Zhang K., Jordan P.M., Bilancia R., Wang W., Börner F., Hofstetter K., Potenza M., Kretzer C., Gerstmeier G., Fischer D., Lorkowski S., Gilbert N.C., Newcomer M.E., Rossi A., Chen X., Werz O. (2021) Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators. Pharmacological Research, doi: 10.1016/j.phrs.2021.105556.


Rajan K, Brinkhaus HO, Sorokina M, Zielesny A, Steinbeck C (2021) DECIMER‑Segmentation: Automated extraction of chemical structure depictions from scientific literature. J Cheminform 13: 20. https://jcheminf.biomedcentral.com/articles/10.1186/s13321-021-00496-1


Schalk F, Gostinčar C, Kreuzenbeck NB, Conlon BH, Sommerwerk E, Rabe P, Burkhardt I, Krüger T, Kniemeyer O, Brakhage AA, Gunde-Cimerman N, de Beer ZW, Dickschat JS, Poulsen M, Beemelmanns C (2021) The termite fungal cultivar Termitomyces combines diverse enzymes and oxidative reactions for plant biomass conversion, mBio 12: e03551-20


Schalk F, Fricke J, Um S, Conlon BH, Maus H, Jäger N, Heinzel T, Schirmeister T, Poulsen M, Beemelmanns C (2021) GNPS-guided discovery of xylacremolide C and D, evaluation of their putative biosynthetic origin and bioactivity studies of xylacremolide A and B. RSC Adv. 11: 18748–18756.


Schädel P., Troisi F., Czapka A., Gebert N., Pace S., Ori A., Werz O. (2021) Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice. The FASEB Journal, doi.org/10.1096/fj.202002684R


Scharf DH, Chankhamjon P, Scherlach K, Dworschak J, Heinekamp T, Roth M, Brakhage AA, Hertweck C (2021) N-Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase. ChemBioChem 27:336-339. doi:10.1002/cbic.202000550


Schaub, J; Zielesny, A; Steinbeck, C; Sorokina, M (2021) Description and Analysis of Glycosidic Residues in the Largest Open Natural Products Database. Biomolecules 11: 486. https://doi.org/10.3390/biom11040486


Scherlach K, Hertweck C (2021) Mining and unearthing hidden biosynthetic potential. Nat. Commun. doi:10.1038/s41467-021-24133-5


Sorokina M, Merseburger P, Rajan K, Yirik MA, Steinbeck C (2021) COCONUT online: Collection of Open Natural Products database. J ChemInform 13:2. https://doi.org/10.1186/s13321-020-00478-9


Stock F, Cirri E, Nuwanthi S, Stock W, Ueberschaar N, Mangelinckx S, Pohnert G, Vyverman W (2021) Sampling, separation, and quantification of N-acyl homoserine lactones from marine intertidal sediments. Limnol Oceanogr Meth 19: 145-157. doi:10.1002/lom3.10412


Traxler L, Wollenberg A, Steinhauser G, Chyzhevskyi I, Dubchak S, Großmann S, Günther A, Gupta DK, Iwannek K-H, Kirieiev S, Lehmann F, Schulz W, Walther C, Raff J, Kothe E (2021) Survival of the basidiomycete Schizophyllum commune in soil under hostile environmental conditions in the Chernobyl Exclusion Zone. Journal of Hazardous Materials 403:124002


Um S, Seibel E, Schalk F, Balluff S, Beemelmanns C (2021) Targeted Isolation of Saalfelduracin B−D from Amycolatopsis saalfeldensis Using LC-MS/MS-Based Molecular Networking. J. Nat. Prod. 84: 1002-1011.


Um S, Guo H, Thiengmag S, Benndorf R, Murphy R, Rischer M, Braga D, Poulsen M, de Beer ZW, Lackner G, Beemelmanns C (2021) Comparative Genomic and Metabolic Analysis of Streptomyces sp. RB110 Morphotypes Illuminates Genomic Rearrangements and Formation of a New 46-Membered Antimicrobial Macrolide. ACS Chem Biol. https://doi.org/10.1021/acschembio.1c00357.


Vallet M, Kaftan F, Grabe V, Ghaderiardakani F, Fenizia S, Svatoš A, Pohnert G, Wichard T (2021) A new glance at the chemosphere of macroalgal–bacterial interactions: In situ profiling of metabolites in symbiosis by mass spectrometry. Beilstein J. Org. Chem. 17: 1313–1322.


Willems S., Gellrich L., Chaikuad A., Kluge S., Werz O., Heering J., Knapp S., Lorkowski S., Schubert-Zsilavecz M., Merk D. (2021) Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions. Cell Chem Biol, S2451-9456(21)00212-9. doi: 10.1016/j.chembiol.2021.04.019.


Yan C, Muhammad R H, Liang D, Reichelt M, Mithöfer A, Scholz SS,Oelmüller R, Chen F. (2021) Food Chem. 22:129671


Zhang K., Pace S., Jordan P.M., Peltner L.K., Weber A., Fischer D., Hofstetter R.K., Chen X., Werz O. (2021) Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides. Biomolecules, 11(5), 746. doi: 10.3390/biom11050746


Zhang S, Mukherji R, Chowdhury S, Reimer L, Stallforth P (2021) Lipopeptide-mediated bacterial interaction enables cooperative predator defense. Prod. Natl. Acad. U.S.A. 118: e2013759118.


                                                                            2020


Abdulsalam O, Wagner K, Wirth S, Kunert M, David A, Kallenbach M, Boland W, Kothe E, Krause K (2020) Phytohormones and volatile organic compounds, like geosmin, in the ectomycorrhiza of Tricholoma vaccinum and Norway spruce (Picea abies). Mycorrhiza. https://doi.org/10.1007/s00572-020-01005-2


Alsufyani T, Califano G, Deicke M, Grueneberg J, Weiss A, Engelen AH, Kwantes M, Mohr JF, Ulrich JF, Wichard T (2020) Macroalgal–bacterial interactions: identification and role of thallusin in morphogenesis of the seaweed Ulva (Chlorophyta). J. Exp. Bot.71: 3340-3349.


Benndorf R, Martin K, Küfner M, De Beer ZW, Vollmers J, Kaster A, Beemelmanns C (2020a) Actinomadura rubteroloni sp. nov. and Actinomadura macrotermitis sp. nov., isolated from the gut of the fungus growing-termite Macrotermes natalensis. Int J Syst Evol Microbiol. doi:10.1099/ijsem.0.004403


Benndorf R, Schwitalla JW, Martin K, De Beer ZW, Vollmers J, Kaster A, Poulsen M, Beemelmanns C (2020b) Nocardia macrotermitis sp. nov. and Nocardia aurantia sp. nov., isolated from the gut of the fungus-growing termite Macrotermes natalensis. Int J Syst Evol Microbiol. doi:10.1099/ijsem.0.004398


Blei F, Dörner S, Fricke J, Baldeweg F, Trottmann F, Komor A, Meyer F, Hertweck C, Hoffmeister D (2020) Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in 'Magic' Mushrooms. Chem. Eur.J. 26: 729-734.


Califano G, Kwantes M, Abreu MH, Costa R, Wichard T (2020) Cultivating the Macroalgal Holobiont: Effects of Integrated Multi-Trophic Aquaculture on the Microbiome of Ulva rigida (Chlorophyta). Front Mar Sci 7. https://www.frontiersin.org/articles/10.3389/fmars.2020.00052/full


Cerqua I, Terlizzi M, Bilancia R, Riemma MA, Citi V, Martelli A, Pace S, Spaziano G, D'Agostino B, Werz O, Ialenti A, Sorrentino R, Cirino G, Rossi A, Roviezzo F (2020) 5 alpha-dihydrotestosterone abrogates sex bias in asthma like features in the mouse. Pharmacol Res 158:10. doi:10.1016/j.phrs.2020.104905


Cooper RE, Wegner C-E, Kügler S, Poulin RX, Ueberschaar N, Wurlitzer JD, Stettin D, Wichard T, Pohnert G, Küsel K (2020) Iron is not everything: unexpected complex metabolic responses between iron-cycling microorganisms. ISME J. 14: 2675-2690.


Cooper R, Wegner C-E, McAllister SM, Shevchenko O, Chan CS, Küsel K (2020) Draft genome sequence of Sideroxydans sp. Strain CL21, an Fe(II)-Oxidizing Bacterium. Microbiol. Res. Announc. 9:e01444-19.


Cortes Llorca L, Li R, Yon F, Schäfer M, Halitschke R, Robert CAM, Kim S-G, Baldwin IT (2020) ZEITLUPE facilitates the rhythmic movements of Nicotiana attenuata flowers. The Plant Journal 103:308-322. doi:10.1111/tpj.14732


Demmler R, Fricke J, Dorner S, Gressler M, Hoffmeister D (2020) S-Adenosyl-l-Methionine Salvage Impacts Psilocybin Formation in "Magic" Mushrooms. Chembiochem 21 (9):1364-1371. doi:10.1002/cbic.201900649


Dose B, Ross C, Niehs SP, Scherlach K, Bauer JP, Hertweck C (2020) Food-Poisoning Bacteria Employ a Citrate Synthase and a Type II NRPS to Synthesize Bolaamphiphilic Lipopeptide Antibiotics. Angew Chem Int Ed. doi: 10.1002/anie.202009107


Ewald J, Sieber P, Garde R, Lang SN, Schuster S, Ibrahim B (2020) Trends in mathematical modeling of host–pathogen interactions. Cell. Mol. Life Sci. 77: 467–480.


Freund RRA, van der Borg M, Gaissmaier D, Schlosser R, Jacob T, Arndt H (2020) Cornforth–Evans transition states in stereocontrolled allylborations of epoxy aldehydes. Chem. Eur. J. 26: 8639-8650.


Fricke J, Kargbo R, Regestein L, Lenz C, Peschel G, Rosenbaum MA, Sherwood A, Hoffmeister D (2020) Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin. Chem Eur J. doi:doi.org/10.1002/chem.202000134


Garde R, Ibrahim B, Kovacs AT, Schuster S (2020) Differential equation-based minimal model describing metabolic oscillations in Bacillus subtilis biofilms. R Soc Open Sci 7 (2):14.


Garde R, Ibrahim B, Schuster S (2020) Extending the minimal model of metabolic oscillations in Bacillus subtilis biofilms. Sci. Rep. 10:5579.


Gama S, Hermenau R, Frontauria M, Milea D, Sammartano S, Hertweck C, Plass W (2020) Iron coordination properties of gramibactin as model for the new class of diazeniumdiolate based siderophores. Chemistry - A European Journal. doi:10.1002/chem.202003842


Ghaderiardakani F, Quartino ML, Wichard T (2020) Microbiome-Dependent Adaptation of Seaweeds Under Environmental Stresses: A Perspective. Front Mar Sci 7:575228. doi:10.3389/fmars.2020.575228


Gebser B, Thume K, Steinke M, Pohnert G (2020) Phytoplankton-derived zwitterionic gonyol and dimethylsulfonioacetate interfere with microbial dimethylsulfoniopropionate sulfur cycling. MicrobiologyOpen:14. doi:10.1002/mbo3.1014


Gilbert NC, Gerstmeier J, Schexnaydre EE, Börner F, Garscha U, Neau DB, Werz O, Newcomer ME (2020) Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nat. Chem. Biol. 16: 783-790.


Gressler M, Löhr NA, Schäfer T, Lawrinowith S, Seibold PS, Hoffmeister D (2020) Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota. Nat Prod Rep. doi:10.1039/d0np00077a


Guo H, Schwitalla JW, Benndorf R, Baunach M, Steinbeck C, Görls H, De Beer ZW, Regestein L, Beemelmanns C (2020) Gene Cluster Activation in a Bacterial Symbiont Leads to Halogenated Angucyclic Maduralactomycins and Spirocyclic Actinospirols. Org Lett. 22: 2634-2638.


Hermenau R, Kugel S, Komor AK, Hertweck C (2020) Helper bacteria halt and disarm mushroom pathogens by linearizing structurally diverse cyclolipopeptides. Proc. Natl. Acad. Sci. U.S.A. 117: 23802-23806.


Jagusch H, Baumeister TUH, Pohnert G (2020) Mammalian-Like Inflammatory and Pro-Resolving Oxylipins in Marine Algae. ChemBioChem. doi:10.1002/cbic.202000178


Jordan PM, Gerstmeier J, Pace S, Bilancia R, Rao Z, Börner F, Miek L, Gutierrez-Gutierrez O, Arakandy V, Rossi A, Ialenti A, Gonzales-Estevez C, Löffler B, Tuchscherr L, Serhan CN, Werz O (2020) Staphylococcus aureus-Derived a-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution. Cell Rep. 33:108247.


Koeberle SC, Gollowitzer A, Laoukili J, Kranenburg O, Werz O, Koeberle A, Kipp AP (2020) Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-kappa B-driven inflammation through redox-active mechanisms. Redox Biology 28. doi:10.1016/j.redox.2019.101388


Krause K, Jung EM, Lindner J, Hardiman I, Poetschner J, Madhavan S, Matthaus C, Kai M, Menezes RC, Popp J, Svatos A, Kothe E (2020) Response of the wood-decay fungus Schizophyllum commune to co-occurring microorganisms. PLOS One 15: e0232145


Krespach MKC, Garcia-Altares M, Flak M, Schoeler H, Scherlach K, Netzker T, Schmalzl A, Mattern DJ, Schroeckh V, Komor A, Mittag M, Hertweck C, Brakhage AA (2020) Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulans protects algal cells from bacteria. ISME J. 14: 2794–2805.


Krespach MKC, Stroe MC, Brakhage AA (2020) Mikrobielle Kommunikation. Warum Mikroorganismen Naturstoffe produzieren. Biospektrum 7:731-733


Kügler S, Cooper R, Boessneck J, Küsel K, Wichard T (2020) Rhizobactin B is the preferred siderophore by a novel Pseudomonas isolate to obtain iron from dissolved organic matter in peatlands. Biometals. 33: 415-433.


Kuhlisch C, Althammer J, Sazhin AF, Jakobsen HH, Nejstgaard JC, Pohnert G (2020) Metabolomics-derived marker metabolites to characterize Phaeocystis pouchetii physiology in natural plankton communities. Sci Rep 10 :14. doi:10.1038/s41598-020-77169-w


Lee SR, Kreuzenberg N, Jang M, Oh T, Ko S-K, Ahn JS, Beemelmanns C, Kim KH (2020) Xyloneside A: a new glycosylated incisterol derivative from Xylaria sp. FB. ChemBioChem. doi:10.1002/cbic.202000065


Lenz C, Sherwood A, Kargbo R, Hoffmeister D (2020) Taking Different Roads: L-Tryptophan as the Origin of Psilocybe Natural Products. ChemPlusChem. doi:10.1002/cplu.202000581


Lenz C, Wick J, Braga D, Garcia-Altares M, Lackner G, Hertweck C, Gressler M, Hoffmeister D (2020) Injury-Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms. Angew. Chem. Int. Ed. 59: 1450-1454.


Li D, Halitschke R, Baldwin IT, Gaquerel E (2020) Information theory tests critical predictions of plant defense theory for specialized metabolism. Sci Adv 6: eaaz0381


Liening S, Fischer J, Jagusch H, Pohnert G, Höcker O, Neusüß C, Werz O, Scriba GKE, Garscha U (2020) 12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets. Prostaglandins and Other Lipid Mediators 152:106480. https://doi.org/10.1016/j.prostaglandins.2020.106480


Li Q, Cooper RE, Wegner CE, Küsel K (2020) Molecular Mechanisms Underpinning Aggregation in Acidiphilium sp. C61 Isolated from Iron‐Rich Pelagic Aggregates. Microorganisms 8:314.


Li S, Joo Y, Cao D, Li R, Lee G, Halitschke R, Baldwin G, Baldwin IT, Wang M (2020) Strigolactone signaling regulates specialized metabolism in tobacco stems and interactions with stem-feeding herbivores. PLoS Biology 18:e3000830. doi:10.1371/journal.pbio.3000830


Malka O, Easson M, Paetz C, Götz M, Reichelt M, Stein B, Luck K, Stanisic A, Juravel K, Santos-Garcia D, Mondaca LL, Springate S, Colvin J, Winter S, Gershenzon J, Morin S, Vassao DG (2020) Glucosylation prevents plant defense activation in phloem-feeding insects. Nat Chem Biol. doi:https://doi.org/10.1038/s41589-020-00658-6


Mohr J.F., Weiss A., Roy S., Wichard T. (2020). Genome sequence of Frankia sp. strain CH37, a metallophore-producing, nitrogen-fixing actinobacterium isolated from the sea buckthorn, Hippophae rhamnoides (Elaeagnaceae). Microbiology Resource Announcement 9: e01184-20. doi: 10.1128/MRA.01184-20


Napagoda M, Gerstmeier J, Butschek H, De Soyza S, Pace S, Lorenz S, Qader M, Witharana S, Nagahawatte A, Wijayaratne G, Svatos A, Jayasinghe L, Koeberle A, Werz O (2020) The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka. Molecules 25 (8). doi:10.3390/molecules25081894


Niehs SP, Dose B, Richter S, Pidot SJ, Dahse HM, Stinear TP, Hertweck C (2020) Mining Symbionts of Spider-Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones. Angew. Chem. Int. Ed. 59: 7766-7771.


Niehs S, Kumpfmüller J, Dose B, Little R, Ishida K, Florez L, Kaltenpoth M, Hertweck C (2020) Insect-Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non-Canonical Polyketide Chain Termination. Angew. Chem. Int. Ed. 59: 23122-23126.


Pace S, Werz O (2020) Impact of Androgens on Inflammation-Related Lipid Mediator Biosynthesis in Innate Immune Cells. frontiers in Immunology. doi:10.3389/fimmu.2020.01356


Pena-Ortiz L, Graca AP, Guo HJ, Braga D, Kollner TG, Regestein L, Beemelmanns C, Lackner G (2020) Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF. Chem Sci 11 (20):5182-5190. doi:10.1039/d0sc01172j


Polikovsky M, Califano G, Dunger N, Wichard T, Golberg A (2020) Engineering bacteria-seaweed symbioses for modulating the photosynthate content of Ulva (Chlorophyta): Significant for the feedstock of bioethanol production. Algal Res. 49:101945.


Rak Lee S, Schalk F, Schwitalla J, Benndorf R, Vollmers J, Kaster A, de Beer Z, Park M, Ahn M, Jung W, Beemelmanns C, Kim K (2020) Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99. J. Nat. Prod. 83: 3102-3110.


Rao Z, Jordan PM, Wang Y, Menche D, Pace S, Gerstmeier J, Werz O (2020) Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes. Biochemical Pharmacology 175:113858. https://doi.org/10.1016/j.bcp.2020.113858


Schalk F, Um S, Guo HJ, Kreuzenbeck NB, Görls H, de Beer W, Beemelmanns C (2020) Targeted Discovery of Tetrapeptides and Cyclic Polyketide- Peptide Hybrids from a Fungal Antagonist of Farming Termites. ChemBioChem 21: 2991-2996.


Schaub J, Zielesny A, Steinbeck C, Sorokina M (2020) Too sweet: cheminformatics for deglycosylation in natural products. J ChemInform 12:67. https://doi.org/10.1186/s13321-020-00467-y


Scherlach K, Hertweck C (2020) Chemical Mediators at the Bacterial-Fungal Interface. Annu. Rev. Microbiol 74: 267-290.


Schwitalla JW, Benndorf R, Martin K, Vollmers J, Kaster A, De Beer ZW, Poulsen M, Beemelmanns C (2020) Streptomyces smaragdinus sp. nov., isolated from the gut of the fungus growing-termite Macrotermes natalensis. Int. J. Syst. Evol. Microbiol. 70: 5806-5811.


Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li YS, Soehnlein O, Shimizu T, Werz O, Chiurchiu V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Sarndahl E, Repsilber D, Kruse R, Sala A, Haeggstrom JZ, Levy BD, Filep JG, Wolkenhauer O (2020) The Atlas of Inflammation Resolution (AIR). Molecular Aspects of Medicine 74. doi:10.1016/j.mam.2020.100894


Sontowski R, Van Dam NM (2020) Functional Variation in Dipteran Gut Bacterial Communities in Relation to Their Diet, Life Cycle Stage and Habitat. insects 11:543.


Sorokina M, Steinbeck C (2020) Review on natural products databases: where to find data in 2020. J Cheminform. 12: 1-51.


Stroe M, Netzker T, Scherlach K, Krüger T, Hertweck C, Valiante V, Brakhage A (2020) Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin. eLife 9: e52541.


Sun R, Gols R, Harey J, Reichelt M, Gershenzon J, Pandit SS, Vassao DG (2020) Detoxification of plant defensive glucosinolates by an herbivorous caterpillar is beneficial to its endoparasitic wasp. Molecular Ecology. doi:10.1111/mec.15613


Then A, Macha K, Ibrahin B, Schuster S (2020) A novel method for achieving an optimal classification of the proteinogenic amino acids. Sci Rep 10:15321. doi:https://www.nature.com/articles/s41598-020-72174-5


Touw AJ, Mogena AV, Maedicke A, Sontowski R, van Dam NM, Tsunoda T (2019) Both biosynthesis and transport are involved in glucosinolate accumulation during root-herbivory in Brassica rapa. Front Plant Sci 10 https://doi.org/10.3389/fpls.2019.01653


Trottmann F, Ishida K, Franke J, Stanisic A, Ishida-Ito M, Kries H, Pohnert G, Hertweck C (2020) Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor. Angew. Chem. Int. Ed. 132: 13613-13617.


Tseng Y-H, Rouina H, Groten K, Rajani P, Furch ACU, Reichelt M, Baldwin IT, Nataraja KN, Shaanker RU, Oelmüller R (2020) An Endophytic Trichoderma Strain Promotes Growth of Its Hosts and Defends Against Pathogen Attack. Front Plant Sci. 11: 573670


Werner M, Pace S, Czapka A, Jordan PM, Gerstmeier J, Koeberle A, Werz O (2020) Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis. Cell. Mol. Life Sci. 77: 4365-4378.


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Barchewitz T, Guljamow A, Meissner S, Timm W, Henneberg M, Baumann O, Hagemann M, Dittmann E (2019) Non‐canonical localization of RubisCO under high light conditions in the toxic cyanobacterium Microcystis aeruginosa PCC7806. Environ. Microbiol. 21: 4836-4851.


Bigalke A, Meyer N, Papanikolopoulou LA, Wiltshire KH, Pohnert G (2019) The Algicidal Bacterium Kordia algicida Shapes a Natural Plankton Community. Appl. Environ. Microbiol. 85: e02779-18.


Bigalke A, Pohnert G (2019) Algicidal bacteria trigger contrasting responses in model diatom communities of different composition. MicrobiologyOpen 8: e00818. doi:10.1002/mbo3.818


Bondoc K G V, Lembke C, Lang S N, Germerodt S, Schuster S, Vyverman W, Pohnert G (2019) Decision-making of the benthic diatom Seminavis robusta searching for inorganic nutrients and pheromones. The ISME Journal. 13 :537-546.


Braga D, Last D, Hasan M, Guo HJ, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G (2019) Metabolic Pathway Rerouting in Paraburkholderia rhizoxinica Evolved Long-Overlooked Derivatives of Coenzyme F-420. Acs Chemical Biology 14 (9):2088-2094. doi:10.1021/acschembio.9b00605


Burkhardt I, Kreuzenbeck NB, Beemelmanns C, Dickschat JS (2019) Mechanistic characterization of three sesquiterpene synthases from the termiteassociated fungus Termitomyces. Org Biomol Chem. 17: 3348-3355.


Conlon BH, Aanen DK, Beemelmanns C, de Beer ZW, de Fine Licht HH, Gunde-Cimerman N, Schiott M, Poulsen M (2019) Reviewing the taxonomy of Podaxis: Opportunities for understanding extreme fungal lifestyles. Fungal Biol 123:183-187


Costa JH, Wassano CI, Angolini CFF, Scherlach K, Hertweck C, Fill TP (2019) Antifungal potential of secondary metabolites involved in the interaction between citrus pathogens. Scientific Reports 9. doi:10.1038/s41598-019-55204-9


Dehm D, Krumbholz J, Baunach M, Wiebach V, Hinrichs K, Guljamow A, Tabuchi T, Jenke-Kodama H, Süssmuth RD, Dittmann E (2019) Unlocking the spatial control of secondary metabolism uncovers hidden natural product diversity in Nostoc punctiforme. ACS Chem. Biol.14: 1271-1279.


Deicke M, Mohr JF, Roy S, Herzsprung P, Bellenger J-P, Wichard T (2019) Metallophore profiling of nitrogen-fixing Frankia spp. to understand metal management in the rhizosphere of actinorhizal plants. Metallomics. doi:10.1039/c8mt00344k


Dörfer M, Gressler M, Hoffmeister D (2019) Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products. Mycol Prog 18 (8):1027-1037. doi:10.1007/s11557-019-01508-z


Dörfer M, Heine D, König S, Gore S, Werz O, Hertweck C, Gressler M, Hoffmeister D (2019) Melleolides impact fungal translation via Elongation Factor 2. Org. Biomol. Chem. 17: 4906-4916.


Egbert MD, Gruenert G, Ibrahim B, Dittrich P (2019) Combining evolution and self-organization to find natural Boolean representations in unconventional computational media. Biosystems 184:11. doi:10.1016/j.biosystems.2019.104011


Fischer D, Gessner G, Fill TP, Barnett R, Tron K, Dornblut K, Kloss F, Stallforth P, Hube B, Heinemann SH, Hertweck C, Scherlach K, Brunke S (2019) Disruption of Membrane Integrity by the Bacterium-Derived Antifungal Jagaricin. Antimicrob. Agents Chemother. 63: e00707-19.


Freund RRA, Gobrecht P, Fischer D, Arndt HD (2019) Advances in chemistry and bioactivity of parthenolide. Nat Prod Reports. doi:10.1039/c9np00049f


Freund RRA, Gobrecht P, Rao Z, Gerstmeier J, Schlosser R, Görls H, Werz O, Fischer D, Arndt HD (2019) Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity. Chem. Sci. 10: 7358-7364.


Fricke J, Lenz C, Wick J, Blei F, Hoffmeister D (2019) Production Options for Psilocybin: Making of the Magic. Chem-Eur J 25 (4):897-903. doi:10.1002/chem.201802758


Fricke J, Sherwood A, Kargbo R, Orry A, Blei F, Naschberger A, Rupp B, Hoffmeister D (2019) Enzymatic Route toward 6-Methylated Baeocystin and Psilocybin. Chembiochem 20 (22):2824-2829. doi:10.1002/cbic.201900358


Götze S, Arp J, Lackner G, Zhang S, Kries H, Klapper M, Garcia-Altares M, Willing K, Günther M, Stallforth P (2019) Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases. Chem. Sci.10: 10979-10990.


Ghaderiardakani F, Califano G, Mohr JF, Abreu MH, Coates JC, Wichard T (2019) Analysis of algal growth- and morphogenesispromoting factors in an integrated multi-trophic aquaculture system for farming Ulva spp. Aquac. Environ. Interact. 11: 375-391


Hädrich A, Taillefert M, Akob D, Cooper RE, Litzba U, Wagner F, Nietzsche S, Ciobota V, Rösch P, Popp J, Küsel K (2019) Microbial Fe(II) oxidation by Sideroxydans lithotrophicus ES-1 in the presence of Schlöppnerbrunnen fen-derived humic acids. FEMS Microbiol Ecol. 95: 1-19.


He J, Fandino RA, Halitschke R, Luck K, Köllner TG, Murdock MH, Ray R, Gase K, Knaden M, Baldwin I, Schuman MC (2019) An unbiased approach elucidates variation in (S)-(+)-linalool, a context-specific mediator of a tri-trophic interaction in wild tobacco. PNAS 116: 14651-14660. doi:10.1073/pnas.1818585116


Henze R, Mu C, Puljiz M, Kamaleson N, Huwald J, Halsegrave J, Speroni di Fenizio P, Parker D, Good C, Rowe JE, Ibrahim B, Dittrich P (2019) Multi-scale stochastic organizationoriented coarse-graining exemplified on the human mitotic checkpoint. Sci Rep 9:3902. https://doi.org/10.1038/s41598-019-40648-w


Hermenau R, Mehl JL, Ishida K, Dose B, Pidot SI, Stinear TP, Hertweck C (2019) Genomics-Driven Discovery of NO-Donating Diazeniumdiolate Siderophores in Diverse Plant-Associated Bacteria. Angew Chem Int Ed 58 (37):13024-13029. doi:10.1002/anie.201906326


Jagusch H, Werner M, Okuno T, Yokomizo T, Werz O, Pohnert G (2019) An Alternative Pathway to Leukotriene B4 Enantiomers Involving a 1,8-Diol-Forming Reaction of an Algal Oxylipin. Org Lett.21: 4667-4670.


Jagusch H, Werner M, Werz O, Pohnert G (2019) 15-Hydroperoxy-PGE2 – A Novel Intermediate in Mammalian and Algal Prostaglandin Biosynthesis. Angew. Chem. Int. Ed. 58: 17641-17645.


Johnson JM, Ludwig A, Furch ACU, Mithöfer A, Scholz S, Reichelt M, Oelmüller R (2019) The beneficial root-colonizing fungus Mortierella Hyalina promotes the aerial growth of Arabidopsis and activates Calcium-dependent responses that restrict Alternaria brassicae-induced disease developement in roots. Mol Plant Microbe Interact 32 (3):351-363


Joo Y, Goldberg JK, Chrétien LTS, Kim S-G, Baldwin IT, Schuman MC (2019a) The circadian clock contributes to diurnal patterns of plant indirect defense in nature. J Integrative Plant Biol 61 (8):924-928


Joo Y, Schuman MC, Goldberg JK, Wissgott A, Kim S-G, Baldwin IT (2019b) Herbivory elicits changes in green leaf volatile production via jasmonate signaling and the circadian clock. Plant Cell Environ 42:972-982. doi:10.1111/pce.13474


Kirtzel J, Ueberschaar N, Deckert-Gaudig T, Krause K, Deckert V, Gadd GM, Kothe E (2019) Organic acids, siderophores, enzymes and mechanical pressure for black slate bioweathering with the basidiomycete Schizophyllum commune. Environ Microbiol 22 (4):1535. doi:10.1111/1462-2920.14749


Klapper M, Paschold A, Zhang S, Weigel C, Dahse H-M, Götze S, Pace S, König S, Rao Z, Reimer L, Werz O, Stallforth P (2019) Bioactivity and Mode of Action of Bacterial Tetramic Acids. ACS Chem. Biol. 14: 1693-1697.


Klapper M, Schlabach K, Paschold A, Zhang S, Chowdhury S, Menzel K-D, Rosenbaum MA, Stallforth P (2019) Biosynthesis of Pseudomonas-Derived Butenolides. Angew Chem Int Ed. doi:10.1002/anie.201914154


König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O (2019) Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase. Cell Chem.Biol. 26: 524-534.


König S, Romp E, Krauth V, Rühl M, Dörfer M, Liening S, Hoffmann B, Häfner AK, Steinhilber D, Karas M, Garscha U, Hoffmeister D, Werz O (2019) Melleolides from honey mushroom inhibit 5-lipoxygenase via Cys159. Cell Chem. Biol. 26: 60–70.


Krauße T, Schütze E, Phieler A, Fürst D, Merten M, Büchel G, Kothe E (2019) Changes in element availability induced by sterilization in heavy metal contaminated substrates: A comprehensive study. J Hazard Mater 370: 70-79. doi:10.1016/j.jhazmat.2017.11.008


Kügler S, Cooper RE, Wegner CE, Mohr JF, Wichard T, Küsel K (2018) Iron-organic matter complexes accelerate microbial iron cycling in an iron-rich fen. Sci. Tot. Environ. 646:972-988


Kurth C, Wasmuth I, Wichard T, Pohnert G, Nett M (2019) Algae induce siderophore biosynthesis in the freshwater bacterium Cupriavidus necator H16. Biometals 32 (1):77-88. doi:10.1007/s10534-018-0159-6


Meents AK, Furch ACU, Almeida-Trapp M, Özyürek S, Scholz SS, Kirbis A, Lenser T, Theißen G, Grabe V, Hansson B, Mithöfer A, Oelmuller R (2019) Beneficial and Pathogenic Arabidopsis Root-Interacting Fungi Differently Affect Auxin Levels and Responsive Genes During Early Infection. Front Microbiol 10: 380


Meents AK, Ozyurek S, Oelmuller R, Furch ACU (2019) Fungal-Induced Formation of Auxin Maxima in Arabidopsis thaliana Roots. Russ J Plant Physiol 66 (6):872-883. doi:10.1134/s102144371907001x


Murry R, Kniemeyer O, Krause K, Saiardi A, Kothe E (2019) Crosstalk between Ras and inositol phosphate signal revealed lithium action on inositol monophosphatase in Schizophyllum commune. Adv. Biol. Regul. 72: 78-88.


Niehs SP, Dose B, Scherlach K, Pidot SJ, Stinear TP, Hertweck C (2019) Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis. Acs Chemical Biology 14 (8):1811-1818. doi:10.1021/acschembio.9b00406


Oberheide A, Pflanze S, Stallforth P, Arndt HD (2019) Solid-Phase-Based Total Synthesis and Stereochemical Assignment of the Cryptic Natural Product Aurantizolicin. Org. Lett. 21: 729-732.


Otani S, Challinor VL, Kreuzenbeck NB, Kildgaard S, Christensen S, Larsen L, Aanen DK, Rasmussen SA, Beemelmanns C, Poulsen M (2019) Disease-free monoculture farming by fungus-growing termites. Sci Rep 9:8819


Pancrace C, Ishida K, Briand E, Pichi DG, Weiz AR, Guljamow A, Scalvenzi T, Sassoon N, Hertweck C, Dittmann E, Gugger M (2018) Unique Biosynthetic Pathway in Bloom-Forming Cyanobacterial Genus Microcystis Jointly Assembles Cytotoxic Aeruginoguanidines and Microguanidines. ACS Chem. Biol. 14: 67-75.


Poulin RX, Pohnert G (2019) Simplifying the complex: metabolomics approaches in chemical ecology. Ana.l Bioanal. Chem. 411: 13-19.


Peter S, Hölzer M, Lamkiewicz K, Speroni di Fenizio P, Al Hwaeer H, Marz M, Schuster S, Dittrich P, Ibrahim B (2019) Structure and Hierarchy of Influenza Virus Models Revealed by Reaction Network Analysis. Viruses 11:449. doi:10.3390/v11050449


Rao Z, Pace S, Jordan PM, Bilancia R, Troisi F, Börner F, Andreas N, Kamradt T, Menche D, Rossi A, Serhan CN, Gerstmeier J, Werz O (2019) Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation. J Immunol. 203:1031-1043.


Ray R, Li D, Halitschke R, Baldwin IT (2019) Using natural variation to achieve a whole-plant functional understanding of the responses mediated by jasmonate signaling. The Plant Journal 99:414-425. doi:10.1111/tpj.14331


Romp E, Arakandy V, Fischer J, Wolz C, Siegmund A, Loffler B, Tuchscherr L, Werz O, Garscha U (2019) Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis. Cellular and Molecular Life Sciences. doi:10.1007/s00018-019-03393-x


Sata M, Berdalet E, Carotenuto Y, Fink P, Herder T, John U, Not F, Pohnert G, Potin P, Selander E, Vyvermann W, Wichard T, Zupo V, Steinke M (2019) Using chemical language to shape future marine health. Front Ecol Environ. doi:doi:10.1002/fee.2113


Sontowski R, Gorringe NJ, Pencs S, Schedl A, Touw AJ, van Dam NM (2019) Same Difference? Low and high glucosinolate Brassica rapa varieties show similar responses upon feeding by two specialist root herbivores. Front Plant Sci 10. https://www.frontiersin.org/articles/10.3389/fpls.2019.01451/


Sorokina M, Steinbeck C (2019) NaPLeS: a natural products likeness scorer—web application and database. J ChemInform 11:55. https://doi.org/10.1186/s13321-019-0378-z


Steinhagen S, Barco A, Wichard T, Weinberger F (2019) CONSPECIFICITY OF THE MODEL ORGANISM ULVA MUTABILIS AND ULVA COMPRESSA (ULVOPHYCEAE, CHLOROPHYTA). J Phycol 55:25-36. doi:10.1111/jpy.12804


Trottmann F, Franke J, Richter I, Ishida K, Cyrulies M, Dahse HM, Regestein L, Hertweck C (2019) Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human- and Animal-Pathogenic Burkholderia Species. Angewandte Chemie-International Edition 58 (40):14129-14133. doi:10.1002/anie.201907324


Werner M, Jordan PM, Romp E, Czapka A, Rao Z, Kretzer C, Koeberle A, Garscha U, Pace S, Claesson H-E, Serhan CN, Werz O, Gerstmeier J (2019) Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome. FASEB J 33. doi:DOI: 10.1096/fj.201802509R


Vallet M, Baumeister TUH, Kaftan F, Grabe V, Buaya A, Thines M, Svatos A, Pohnert G (2019) The oomycete Lagenisma coscinodisci hijacks host alkaloid synthesis during infection of a marine diatom. Nat. Commun. 10: e4938.


Ye W, Jiang JL, Lin YL, Yeh KW, Lai ZX, Xu XM, Oelmuller R (2019) Colonisation of Oncidium orchid roots by the endophyte Piriformospora indica restricts Erwinia chrysanthemi infection, stimulates accumulation of NBS-LRR resistance gene transcripts and represses their targeting micro-RNAs in leaves. BMC Plant Biol 19: 601


Zou Y, Li R, Baldwin IT (2019) ZEITLUPE is required for shade avoidance in the wild tobacco Nicotiana attenuata. J Integr Plant Biol. doi:10.1111/jipb.12880


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Arp J, Götze S, Mukherji R, Mattern DJ, García-Altares M, Klapper M, Brock D, Brakhage A, Strassmann JE, Queller DC, Bardl B, Willing K, Peschel G, Stallforth P (2018) Synergistic activity of cosecreted natural products from amoebae-associated bacteria. Proc. Natl. Acad. Sci. U.S.A. 115: 3758-3763.


Baumeister TUH, Ueberschaar N, Pohnert G (2018) Gas-Phase Chemistry in the GC OrbitrapMass Spectrometer. J Am Soc Mass Spectrom. doi:10.1007/s13361-018-2117-5


Benndorf R, Guo H, Sommerwerk E, Weigel C, Garcia-Altares M, Martin K, Hu H, Kuefner M, de Beer ZW, Poulsen M, Beemelmanns C (2018) Natural products from Actinobacteria associated with fungus-growing termites. Antibiotics 7: 83.


Blei F, Baldeweg F, Fricke J, Hoffmeister D (2018) Biocatalytic production of psilocybin and derivatives in tryptophan synthase-enhanced reactions. Chem Eur J. doi:10.1002/chem.201801047


Blei F, Fricke J, Wick J, Slot JC, Hoffmeister D (2018) Iterative l-Tryptophan Methylation in Psilocybe Evolved by Subdomain Duplication. Chembiochem 19 (20):2160-2166. doi:10.1002/cbic.201800336


Brütting C, Crava CM, Schäfer M, Schuman MC, Meldau S, Adam N, Baldwin IT (2018) Cytokinin transfer by a free-living mirid to Nicotiana attenuata recapitulates a strategy of endophytic insects. eLife 7. doi:

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Cheung S-Y, Werner M, Esposito L, Troisi F, Cantone V, Liening S, König S, Gerstmeier J, Koeberle A, Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke T, Pace S (2018) Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation. Eur J Med Chem 156:815-830


De Clerck O, Kao S-M, Bogaert KA, ..., Van de Peer Y, Wichard T, Bothwell JH (2018) Insights into the Evolution of Multicellularity from the Sea Lettuce Genome. Current  Biology 28:2921-2933


Dose B, Niehs SP, Scherlach K, Florez LV, Kaltenpoth M, Hertweck C (2018) Unexpected Bacterial Origin of the Antibiotic Icosalide: Two-Tailed Depsipeptide Assembly in Multifarious Burkholderia Symbionts. ACS Chem Biol 13:2414-2420


Englert C, Nischang I, Bader C, Borchers P, Alex J, Pröhl M, Hentschel M, Hartlieb M, Traeger A, Pohnert G, Schubert S, Gottschaldt M, Schubert US (2018) Photocontrolled Release of Chemicals from Nano- and Microparticle Containers. Angew Chem Int Ed 57:2479 –2482


Fischer J, Müller SY, Netzker T, Jäger T, Gacek-Matthews A, Scherlach K, Stroe MC, Garcia-Altares M, Pezzini F, Schoeler H, Reichelt M, Gershenzon J, Krespach MKC, Shelest E, Schroeckh V, Valiante V, Heinzel T, Hertweck C, Strauss J, Brakhage AA (2018) Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites. eLife 7: e40969


Florez LV, Scherlach K, Miller IJ, Rodrigues A, Kwan JC, Hertweck C, Kaltenpoth M (2018) An antifungal polyketide associated with horizontally acquired genes supports symbiontmediated defense in Lagria villosa beetles. Nat. Commun.9: 2478.


Gama S, Frontauria M, Ueberschaar N, Brancato G, Milea D, Sammartano S, Plass W (2018) Thermodynamic study on 8-hydroxyquinoline-2-carboxylic acid as a chelating agent for iron found in the gut of Noctuid larvae. New J Chem 42:8062 - 8073


Guo H, Benndorf R, König S, Leichniz D, Weigel C, Peschel G, Berthel P, Kaiser M, Steinbeck C, Werz O, Poulsen M, Beemelmanns C (2018) Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS-derived Pyrans. Chem. Eur. J. 24: 11319-11324.


Guo H, Roman D, Beemelmanns C (2018) Tropolone natural products. Nat Prod Reports. doi:10.1039/c8np00078f


Guo H, Schmidt A, Stephan P, Raguz L, Braga D, Kaiser M, Dahse H, Weigel C, Lackner G, Beemelmanns C (2018) Precursor-Directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins. ChemBioChem 19:2307-2311.


Heimerl N, Hommel E, Westermann M, Meichsner D, Lohr M, Hertweck C, Grossman AR, Mittag M, Sasso S (2018) A giant type I polyketide synthase participates in zygospore maturation in Chlamydomonas reinhardtii. Plant J. 95: 268-281


Heine D, Holmes NA, Worsley SF, Santos ACA, Innocent TM, Scherlach K, Patrick EH, Yu D, W, Murell JC, Vieria PC, Boomsma J, Hertweck C, Hutchings MI, Wilkinson B (2018) Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen. Nat Commun. doi:10.1038/s41467-018-04520-1


Hermenau R, Ishida K, Gama S, Hoffmann B, Pfeifer-Leeg M, Plass W, Mohr JF, Wichard T, Saluz H-P, Hertweck C (2018) Gramibactin is a bacterial siderophore with a diazeniumdiolate ligand system. Nat. Chem. Biol. 14:814-843


Johnson JM, Thürich J, Petutschnig EK, Altschmied L, Meichsner D, Sherameti I, Dindas J, Mrozinska A, Paetz C, Scholz SS, Furch ACU, Lipka V, Hedrich R, Schneider B, Svatos A, Oelmuller R (2018) A Poly(A) Ribonuclease Controls the Cellotriose-Based Interaction between Piriformospora indica and Its Host Arabidopsis. Plant Phys 176:2496-2514


Kessler RW, Weiss A, Kuegler S, Hermes C, Wichard T (2018) Macroalgal–bacterial interactions: Role of dimethylsulfoniopropionate in microbial gardening by Ulva (Chlorophyta). Mol. Ecol. 27: 1808-1819.


Klapper M, Braga D, Lackner G, Herbst R, Stallforth P (2018) Bacterial Alkaloid Biosynthesis: Structural Diversity via a Minimalistic Nonribosomal Peptide Synthetase. Cell Chem Biol 25:1-7


Koeberle A, Werz O (2018) Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis. Biotech Adv. doi:10.1016/j.biotechadv.2018.02.010


Lembke C, Stettin D, Speck F, Ueberschaar N, De Decker S, Vyverman W, Pohnert G (2018) Attraction Pheromone of The Benthic Diatom Seminavis robusta: Studies on Structure-Activity Relationships. J Chem Ecol 44:354-363


Li J, Schuman MC, Halitschke R, Li X, Guo H, Grabe V, Hammer A, Baldwin IT (2018) The decoration of specialized metabolites influences stylar development. eLife 7:e38611. doi:10.7554/eLife.38611.


Meyer N, Rettner J, Werner M, Werz O, Pohnert G (2018) Algal Oxylipins Mediate the Resistance of Diatoms against Algicidal Bacteria. Mar Drugs 16:486


Netzker T, Flak M, Krespach MKC, Stroe MC, Weber J, Schroeckh V, Brakhage AA (2018) Microbial interactions trigger the production of antibiotics. Curr. Opin. Microbiol 45: 117-123


Niehs SP, Dose B, Scherlach K, Roth M, Hertweck C (2018a) Genomics-Driven Discovery of a Symbiont-Specific Cyclopeptide from Bacteria Residing in the Rice Seedling Blight Fungus. ChemBioChem 19:2167-2172


Niehs SP, Scherlach K, Hertweck C (2018b) Genomics-driven discovery of a linear lipopeptide promoting host colonization by endofungal bacteria. Org Biomol Chem 16:8345-8352


Pein H, Ville A, Pace S, ..., Werz O, Koeberle A (2018) Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nat. Commun. 9: 3834.


Pohnert G, Poulin RX, Baumeister TUH (2018) The making of a plankton toxin. Science 361:1308


Poulin RX, Pohnert G (2018) Simplifying the complex: metabolomics approaches in chemical ecology. Anal Bioanal Chem. doi: https://doi.org/10.1007/s00216-018-1470-3


Rischer M, Raguz L, Guo H, Keiff F, Diekert G, Goris T, Beemelmanns C (2018) Biosynthesis, Synthesis, and Activities of Barnesin A, a NRPS-PKS  Hybrid Produced by an Anaerobic Epsilonproteobacterium. ACS Chem Biol. doi:10.1021/acschembio.8b00445


Rodrigues T, Werner M, Roth J, da Cruz EHG, Marques MC, Akkapeddi P, Lobo SA, Koeberle A, Corzana F, da Silva Junior EN, Werz O, Bernardes GJL (2018) Machine intelligence decrypts b-lapachone as an allosteric 5-lipoxygenase inhibitor. Chem Sci. doi:10.1039/c8sc02634c


Roessler C, Arndt HD (2018) A Master Switch in Thiopeptide Biosynthesis. Cell Chem Biol 25:121-123. doi:10.1016/j.chembiol.2018.01.017


Sasso S, Stibor H, Mittag M, Grossman AR (2018) From molecular manipulation of domesticated Chlamydomonas reinhardtii to survival in nature. eLife 7: e39233.


Scholz SS, Schmidt-Heck W, Guthke R, Furch ACU, Reichelt M, Gershenzon J, Oelmüller R (2018) Verticillium dahliae-Arabidopsis Interaction Causes Changes in Gene Expression Profiles and Jasmonate Levels on Different Time Scales. Front Microbiol 9:217


Schuman MC, Baldwin IT (2018) Field studies reveal functions of chemical mediators in plant interactions. Chem Soc Rev 47:5338-5353


Tauber JP, Matthaus C, Lenz C, Hoffmeister D, Popp J (2018) Analysis of basidiomycete pigments in situ by Raman spectroscopy. J Biophoton. 11: e201700369.


Thongkongkaew T, Ding W, Bratovanow E, Oueis E, García-Altares M, Zaburannyi N, Harmrolfs K, Zhang Y, Scherlach K, Müller R, Hertweck C (2018) Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species. ACS Chem Biol 13:1370-1379


Thürich J, Meichsner D, Furch ACU, Pfalz J, Krüger T, Kniemeyer O, Brakhage A, Oelmüller (2018) Arabidopsis thaliana responds to colonisation of Piriformospora indica by secretion of symbiosis-specific proteins. PLOS One 13: e0209658


Thume K, Gebser B, Chen L, Meyer N, Kieber DJ, Pohnert G (2018) The metabolite dimethylsulfoxonium propionate extends the marine organosulfur cycle. Nature 563: 412-415.


Vahabi K, Reichelt M, Scholz SS, Furch ACU, Matsuo M, Johnson JM, Sherameti I, Gershenzon J, Oelmuller R (2018) Alternaria Brassicae Induces Systemic Jasmonate Responses in Arabidopsis Which Travel to Neighboring Plants via a Piriformsopora Indica Hyphal Network and Activate Abscisic Acid Responses. Front Plant Sci 9:626


Wang M, Wilde J, Baldwin IT, Groten K (2018) Nicotiana attenuata's capacity to interact with arbuscular mycorrhiza alters its competitive ability and elicits major changes in the leaf transcriptome. J Integr Plant Biol 60:242-261. doi:10.1111/jipb.12609


Werz O, Gerstmeier J, Libreros S, De la Rosa X, Werner M, Norris PC, Chiang N, Serhan C N (2018) Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nat. Commun. 9:59.


Wichard T, Beemelmanns C (2018) Role of Chemical Mediators in Aquatic Interactions across the Prokaryote–Eukaryote Boundary. J Chem Ecol. doi:10.1007/s10886-018-1004-7


                                                                     2017


Adam N, Erler T, Kallenbach M, Kaltenpoth M, Kunert G, Baldwin IT, Schuman MC (2017) Sex ratio of mirid populations shifts in response to hostplant co-infestation or altered cytokinin signaling. J Integr Plant Biol 59 (1):44-59.


Aiyar P, Schaeme D, García-Altares M, Carrasco Flores D, Dathe H, Hertweck C, Sasso S, Mittag M (2017) Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells. Nat Commun  doi: 10.1038/s41467-017-01547-8


Alonso P, Bartram S, Arias-Cordero E, Novoselov A, Halty-deLeon L, Shao Y, Boland W (2017) In vivo isotopic labeling of symbiotic bacteria involved in cellulose degradation and nitrogen recycling within the gut of the forest cockchafer (Melolontha hippocastani). Frontiers Microbiol 8:1970


Alsufyani T, Weiss A, Wichard T (2017) Time Course Exo-Metabolomic Profiling in the Green Marine Macroalga Ulva (Chlorophyta) for Identification of Growth Phase-Dependent Biomarkers. Mar Drugs 15 (1):20.


Bakshi M, Sherameti I, Meichsner D, Thürich J, Varma A, Johri AK, Yeh KW, Oelmüller R (2017) Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol 8:15.


Blin K, Wolf T, Chevrette MG, Lu X, Schwalen CJ, Kautsar SA, Suarez Duran HG, de los Santos ELC, Kim HU, Nave M, Dickschat JS, Mitchell DA, Shelest E, Breitling R, Takano E, Lee SY, Weber T, Medema MH (2017) antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification. Nucleic Acids Res 45 (W1):W36-W41.


Bolanz RM, Grauer C, Cooper R, Göttlicher J, Steininger R, Perry S, Küsel K (2017) Incorporation of molybdenum(VI) in akaganéite (β-FeOOH) and the microbial reduction of Mo–akaganéite by Shewanella loihica PV-4. CrystEngComm 19:6189


Brandt P, García-Altares M, Nett M, Hertweck C, Hoffmeister D (2017) Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase. Angew Chem Int Edit 56:5937-5941.


Cooper RE, Eusterhues K, Wegner CE, Totsche KU, Küsel K (2017) Ferrihydrite associated organic matter (OM) stimulates reduction by Shewanella oneidensis MR-1 and a complex microbial consortia. Biogeosciences Discuss 2017:1-32.


de Vries RP et al. (112 authors including Shelest E and Brakhage AA) (2017) Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. Genome Biol 18:28.


Englert C, Pröhl M, Czaplewska JA, Fritzsche C, Preußger E, Schubert US, Traeger A, Gottschaldt M (2017) D-Fructose-Decorated Poly(ethylene imine) for Human Breast Cancer Cell Targeting. Macromol Biosci doi: 10.1002/mabi.201600502.


Flórez LV, Scherlach K, Gaube P, Ross C, Sitte E, Hermes C, Rodrigues A, Hertweck C, Kaltenpoth M (2017) Antibiotic-producing symbionts dynamically transition between plant pathogenicity and insect-defensive mutualism. Nature Commun 8:15172


Ghaderiardakani F, Coates JC, Wichard T (2017) Bacteria-induced morphogenesis of Ulva intestinalis and Ulva mutabilis (Chlorophyta): a contribution to the lottery theory. FEMS Microbiol Ecol 93 (8):fix094.


Guljamow A, Kreische M, Ishida K, Liaimer A, Altermark B, Bähr L, Hertweck C, Ehwald R, Dittmann E (2017) High-density cultivation of terrestrial Nostoc strains leads to reprogramming of secondary metabolome. Appl Environ Microbiol. doi:0.1128/AEM.01510-17.


Hirth M, Liverani S, Mahlow S, Bouget F-Y, Pohnert G, Sasso S (2017) Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri. Metabolomics 13 (6):68.


Hua MS, Kumar RS, Shyur LF, Cheng YB, Tian Z, Oelmüller R, Yeh KW (2017) Metabolomic profiles delineate symbiotic functions of the root endophytic fungus Piriformospora indica colonizing Chinese cabbage roots. Sci Rep 7 (1):9291. doi:doi: 10.1038/s41598-017-08715-2


Jimenez-Aleman G, Seçinti S, W B (2017a) A succinct access to ω-hydroxylated jasmonates via olefin metathesis. Z Naturforsch 72: 285-292.


Jimenez-Aleman GH, Machado RAR, Baldwin IT, Boland W (2017) JA-Ile-macrolactones uncouple growth and defense in wild tobacco. Org Biomol Chem 15 (16):3391-3395.


Katsaros C, Weiss A, Llangos I, Theodorou I, Wichard T (2017) Cell structure and microtubule organisation during gametogenesis of Ulva mutabilis Føyn (Chlorophyta). Bot Mar 60 (2):123-135.


Kessler RW, Crecelius AC, Schubert US, Wichard T (2017) In situ monitoring of molecular changes during cell differentiation processes in marine macroalgae through mass spectrometric imaging. Anal Bioanal Chem 409 (20):4893-4903.


Kuhlisch C, Deicke M, Ueberschaar N, Wichard T, Pohnert G (2017) A fast and direct liquid chromatography-mass spectrometry method to detect and quantify polyunsaturated aldehydes and polar oxylipins in diatoms. Limnol Oceanogr Meth 15 (1):70-79.


Li R, Wang M, Yang W, Schuman MC, Weinhold A, Schäfer M, Jiménez-Alemán GH, Barthel A, Baldwin IT (2017) Flower-specific jasmonate signaling regulates constitutive floral defenses in wild tobacco. Proc Natl Acad Sci USA 114: E7205-E7214


Lorenz B, Wichmann C, Stöckel S, Rösch P, Popp J (2017) Cultivation-Free Raman Spectroscopic Investigations of Bacteria. Trends Microbiol 25 (5):413-424.


Meier A, Kastner A, Harries D, Wierzbicka-Wieczorek M, Majzlan J, Büchel G, Kothe E (2017a) Calcium carbonates: Induced biomineralization vs. controlled macromorpholoy Biogeosciences 14:4867-4878.


Meier A, Singh M, Kastner A, Merten D, Büchel G, Kothe E (2017b) Microbial communities in carbonate rocks - from soil via groundwater to rocks. J Basic Microbiol:57 752-761.


Meyer N, Bigalke A, Kaulfuß A, Pohnert G (2017) Strategies and ecological roles of algicidal bacteria. FEMS Microbiol Rev. doi:10.1093/femsre/fux029.


Molloy M, Hertweck C (2017) Antimicrobial discovery inspired by ecological interactions. Curr Opin Microbiol doi:10.1016/j.mib.2017.09.006.


Mori JF, Ueberschaar N, Lu S, Cooper RE, Pohnert G, Küsel K (2017) Sticking together: inter-species aggregation of bacteria isolated from iron snow is controlled by chemical signaling. ISME J 11 (5):1075-1086.


Pace S, Pergola C, Dehm F, Rossi A, Gerstmeier J, Troisi F, Pein H, Schaible AM, Weinigel C, Rummler S, Northoff H, Laufer S, Maier TJ, Rådmark O, Samuelsson B, Koeberle A, Sautebin L, Werz O (2017) Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males. J Clin Invest 127 (8):3167-3176.


Pace S, Rossi A, Krauth V, Dehm F, Troisi F, Bilancia R, Weinigel C, Rummler S, Werz O, Sautebin L (2017) Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation. Sci Rep 7:3759.


Pergola C, Schubert K, Pace S, Ziereisen J, Nikels F, Scherer O, Hüttel S, Zahler S, Vollmar AM, Weinigel C, Rummler S, Müller R, Raasch M, Mosig A, Koeberle A, Werz O (2017) Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy. Sci Rep 7:12.


Poreddy S, Li J, Baldwin I (2017) Plant-mediated RNAi silences midgut-expressed genes in congeneric lepidopteran insects in nature. BMC Plant Biol 17:199-209


Schäfer M, Brütting C, Xu S, Ling Z, Steppuhn A, Baldwin IT, Schuman MC (2017) NaMYB8 regulates distinct, optimally distributed herbivore defense traits. J Integr Plant Biol. doi:10.1111/jipb.12593


Scherlach K, Hertweck C (2017) Mediators of mutualistic microbe-microbe interactions. Nat Prod Rep. doi:10.1039/C7NP00035A


Schieferdecker S, König S, Pace S, Werz O, Nett M (2017) Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation. ChemMedChem 12:23-27.


Shao Y, Chen B, Sun C, Ishida K, Hertweck C, Boland W (2017) Symbiont-Derived Antimicrobials Contribute to the Control of the Lepidopteran Gut Microbiota. Cell Chem Biol 24 (1):66-75.


Shelest E (2017) Transcription Factors in Fungi: TFome Dynamics, Three Major Families, and Dual-Specificity TFs. Front Genet 8:53.


Svouraki A, Garscha U, Kouloura E, Pace S, Pergola C, Krauth V, Rossi A, Sautebin L, Halabalaki M, Werz O, Gaboriaud-Kolar N, Skaltsounis AL (2017) Evaluation of Dual 5-Lipoxygenase/Microsomal Prostaglandin E2 Synthase-1 Inhibitory Effect of Natural and Synthetic Acronychia-Type Isoprenylated Acetophenones. J Nat Prod 80 (3):699-706.


Tauber JP, Gallegos-Monterrosa R, Kovács AT, Shelest E, Hoffmeister D (2017) Dissimilar pigment regulation in Serpula lacrymans and Paxillus involutus during inter-kingdom interactions. Microbiology. doi: 10.1099/mic.0.000582


Thomas L, Rao Z, Gerstmeier J, Raasch M, Weinigel C, Rummler S, Menche D, Müller R, Pergola C, Mosig A, Werz O (2017) Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase. Biochem Pharmacol 130:71-82.


Wang M, Schoettner M, Xu S, Paetz C, Wilde J, Baldwin IT, Groten K (2017) Catechol, a major component of smoke, influences primary root growth and root hair elongation through reactive oxygen species-mediated redox signaling. New Phytol 213 (4):1755-1770.


Weiss A, Costa R, Wichard T (2017) Morphogenesis of Ulva mutabilis (Chlorophyta) induced by Maribacter species (Bacteroidetes, Flavobacteriaceae). Bot Mar 60 (2):197-206.


Yildirim T, Matthäus C, Press TP, Schubert S, Bauer M, Popp J, Schubert US (2017) Uptake of Retinoic Acid-Modified PMMA Nanoparticles in LX-2 and Liver Tissue by Raman Imaging and Intravital Microscopy. Macromol Biosci 17:1700064


 

                                                                      2016


Baccile JA, Spraker JE, Le HH, Brandenburger E, Gomez C, Bok JW, Macheleidt J, Brakhage AA, Hoffmeister D, Keller NP, Schroeder FC (2016) Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. Nat Chem Biol 12 (6):419-U470.


Bondoc KGV, Lembke C, Vyverman W, Pohnert G (2016) Searching for a Mate: Pheromone-Directed Movement of the Benthic Diatom Seminavis robusta. Microbial Ecol 72 (2):287-294.


Crava CM, Brütting C, Baldwin IT (2016) Transcriptome profiling reveals differential gene expression of detoxification enzymes in a hemimetabolous tobacco pest after feeding on jasmonate-silenced Nicotiana attenuata plants. BMC Genomics 17:1005.


Englert C, Fevre M, Wojtecki RJ, Cheng W, Xu Q, Yang C, Ke X, Hartlieb M, Kempe K, García JM, Ono RJ, Schubert US, Yang YY, Hedrick JL (2016) Facile carbohydrate-mimetic modifications of poly(ethylene imine) carriers for gene delivery applications. Polym Chem 7 (37):5862-5872.


Englert C, Trützschler AK, Raasch M, Bus T, Borchers P, Mosig AS, Traeger A, Schubert US (2016) Crossing the blood-brain barrier: Glutathione-conjugated poly(ethylene imine) for gene delivery. J Control Release 241:1-14.


Forino M, Pace S, Chianese G, Santagostini L, Werner M, Weinigel C, Rummler S, Fico G, Werz O, Taglialatela-Scafati O (2016) Humudifucol and Bioactive Prenylated Polyphenols from Hop (Humulus lupulus cv. "Cascade"). J Nat Prod 79:590-597.


Gerstmeier J, Newcomer ME, Dennhardt S, Romp E, Fischer J, Werz O, Garscha U (2016) 5-Lipoxygenase-Activating Protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation. FASEB J 30:1892-1900.


Grueneberg J, Engelen A, Costa R, Wichard T (2016) Macroalgal morphogenesis induced by waterborne compounds and bacteria in costal seawater. PLOS One 11 (1):22.


Guo H, Kreuzenbeck NB, Otani S, Garcia-Altares M, Dahse H-M, Weigel C, Aanen DK, Hertweck C, Poulsen M, Beemelmanns C (2016) Pseudoxylallemycins A-F, Cyclic Tetrapeptides with Rare Allenyl Modifications Isolated from Pseudoxylaria sp. X802: A Competitor of Fungus-Growing Termite Cultivars. Org Lett 18 (14):3338-3341.


Heiling S, Khanal S, Barsch A, Zurek G, Baldwin IT, Gaquerel E (2016) Using the knowns to discover the unknowns: MS-based dereplication uncovers structural diversity in 17-hydroxygeranyllinalool diterpene glycoside production in the Solanaceae. Plant J 85 (4):561-577.


Kalb D, Heinekamp T, Schieferdecker S, Nett M, Brakhage AA, Hoffmeister D (2016) An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides. ChemBioChem 17:1813-1817.


Kurth C, Kage H, Nett M (2016) Siderophores as molecular tools in medical and environmental applications. Org Biomol Chem 14:8212-8227.


Kurth C, Schieferdecker S, Athanasopoulou K, Seccareccia I, Nett M (2016) Variochelins, Lipopeptide Siderophores from Variovorax boronicumulans Discovered by Genome Mining. J Nat Prod 79:865-872.


Kusic D, Ramoji A, Neugebauer U, Rösch P, Popp J (2016a) Raman Spectroscopic Characterization of Packaged L-pneumophila Strains Expelled by T-thermophila. Anal Chem 88 (5):2533-2537.


Kusic D, Rösch P, Popp J (2016b) Fast label-free detection of Legionella spp. in biofilms by applying immunomagnetic beads and Raman spectroscopy. Syst Appl Microbiol 39 (2):132-140.


Li D, Heiling S, Baldwin IT, Gaquerel E (2016) Illuminating a plant's tissue-specific metabolic diversity using computational metabolomics and information theory. Proc Natl Acad Sci 113 (47):E7610-E7618.


Liening S, Scriba GKE, Rummler S, Weinigel C, Kleinschmidt TK, Haeggström JZ, Werz O, Garscha U (2016) Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors. Biochim Biophys Acta 1861 (11):1605-1613.


Machado RAR, McClure M, Hervé MR, Baldwin IT, Erb M (2016) Benefits of jasmonate-dependent defenses against vertebrate herbivores in nature. eLife 5:21.


Macheleidt J, Mattern DJ, Fischer J, Netzker T, Weber J, Schroeckh V, Valiante V, Brakhage AA (2016) Regulation and Role of Fungal Secondary Metabolites. Annual Review of Genetics, Vol 50, 371-392.


Netzker T, Schroeckh V, Gregory MA, Flak M, Krespach MKC, Leadlay PF, Brakhage AA (2016) An Efficient Method To Generate Gene Deletion Mutants of the Rapamycin-Producing Bacterium Streptomyces iranensis HM 35. Appl Environ Microbiol 82 (12):3481-3492.


Noumsi JC, Pourhassan N, Darnajoux R, Deicke M, Wichard T, Burrus V, Bellenger J-B (2016) Effect of organic matter on nitrogenase metal cofactors homeostasis in Azotobacter vinelandii under diazotrophic conditions. Environ Microbiol Rep 8:76-84.


Pahlow S, Stöckel S, Pollok S, Cialla-May D, Rösch P, Weber K, Popp J (2016) Rapid identification of Pseudomonas spp. via Raman Spectroscopy Using Pyoverdine as Capture Probe. Anal Chem 88 (3):1570-1577.


Rossi A, Pace S, Tedesco F, Pagano E, Guerra G, Troisi F, Werner M, Roviezzo F, Zjawiony JK, Werz O, Izzo AA, Capasso R (2016) The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation. Pharmacol Res 106:64-71.


Schäfer M, Brütting C, Baldwin IT, Kallenbach M (2016) High-throughput quantification of more than 100 primary- and secondary-metabolites, and phytohormones by a single solid-phase extraction based sample preparation with analysis by UHPLC-HESI-MS/MS. Plant Meth 12:18.


Shelest E, Wingender E (2016) Systems Biology of Transcription Regulation. Front Genet 7:124.


Stöckel S, Kirchhoff J, Neugebauer U, Rösch P, Popp J (2016) The application of Raman spectroscopy for the detection and identification of microorganisms. J Raman Spectrosc 47 (1):89-109.


Tauber JP, Schroeckh V, Shelest E, Brakhage AA, Hoffmeister D (2016) Bacteria induce pigment formation in the basidiomycete Serpula lacrymans. Environ Microbiol 18:5218-5227.


Teh BS, Apel J, Shao Y, Boland W (2016) Colonization of the intestinal tract of the polyphagous pest Spodoptera littoralis with the GFP-tagged indigenous gut bacterium Enterococcus mundtii. Front Microbiol 7:928.


Wichard T (2016) Bakterien-Algen-Interaktionen: Die Grünalge Ulva (Chlorophyta) kommt nur mit den richtigen Bakterien in Form. Rundgespräche Forum Ökologie 45:69-82.


Wichard T (2016) Bakterien-induzierte Morphogenese der marinen Makroalge. Biospektrum 22:585-588.


Wichard T (2016) Identification of Metallophores and Organic Ligands in the Chemosphere of the Marine Macroalga Ulva (Chlorophyta) and at Land-Sea Interfaces. Front Mar Sci 3:131.


Wick J, Heine D, Lackner G, Misiek M, Tauber J, Jagusch H, Hertweck C, Hoffmeister D (2016) A Fivefold Parallelized Biosynthetic Process Secures Chlorination of Armillaria mellea (honey mushroom) Toxins. Appl Environ Microbiol 82 (4):1196-1204.


Wojtas KP, Riedrich M, Lu JY, Winter P, Winkler T, Walter S, Arndt H-D (2016) Total Synthesis of Nosiheptide. Angew Chem Int Edit 55 (33):9772-9776.


Wolf T, Shelest V, Nath N, Shelest E (2016) CASSIS and SMIPS: promoter-based prediction of secondary metabolite gene clusters in eukaryotic genomes. Bioinformatics 32 (8):1138-1143.


 

 

                                                                      2015


Bakshi M, Vahabi K, Bhattacharya S, Sherameti I, Varma A, Yeh KW, Baldwin I, Johri AK, Oelmüller R (2015) WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol 15:19.


Bode HB, Brachmann AO, Jadhav KB, Seyfarth L, Dauth C, Fuchs SW, Kaiser M, Waterfield NR, Sack H, Heinemann SH, Arndt H-D (2015) Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase. Angew Chem Int Edit 54 (35):10352-10355.


Braesel J, Götze S, Shah F, Heine D, Tauber J, Hertweck C, Tunlid A, Stallforth P, Hoffmeister D (2015) Three Redundant Synthetases Secure Redox-Active Pigment Production in the Basidiomycete Paxillus involutus. Chem Biol 22 (10):1325-1334.


Gerstmeier J, Weinigel C, Rummler S, Rådmark O, Werz O, Garscha U (2015) Time-resolved in situ assembly of the leukotriene-synthetic 5-LO / FLAP complex in blood leukocytes. FASEB J 30:276-285.


Hom EFY, Aiyar P, Schaeme D, Mittag M, Sasso S (2015) A Chemical Perspective on Microalgal-Microbial Interactions. Trends Plant Sci 20 (11):689-693.


Korp J, Koenig S, Schieferdecker S, Dahse H-M, Koenig GM, Werz O, Nett M (2015) Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors. ChemBioChem 16:2445-2450.


Kuhlisch C, Pohnert G (2015) Metabolomics in chemical ecology. Nat Prod Rep 32 (7):937-955.


Netzker T, Fischer J, Weber J, Mattern DJ, König CC, Valiante V, Schroeckh V, Brakhage AA (2015) Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters. Front Microbiol 6:13.


Neugebauer U, Rösch P, Popp J (2015) Raman spectroscopy towards clinical application: drug monitoring and pathogen identification. Int J Antimicrob Agents 46:S35-S39.


Novoselov A, Becker T, Pauls G, von Reuss SH, Boland W (2015) Spodoptera littoralis detoxifies neurotoxic 3-nitropropanoic acid by conjugation with amino acids. Insect Biochem Mol Biol 63:97-103.


Oertel W, Wichard T, Weissgerber A (2015) Transformation of Ulva mutabilis (Chlorophyta) by vector plasmids integrating into the genome. J Phycol 51 (5):963-979.


Scherer O, Maess MB, Lindner S, Garscha U, Weinigel C, Rummler S, Werz O, Lorkowski S (2015) A procedure for efficient non-viral siRNA transfection of primary human monocytes using nucleofection. J Immunol Methods 422:118-124.


Schieferdecker S, König S, Koeberle A, Dahse H-M, Werz O, Nett M (2015) Myxochelins Target Human 5-Lipoxygenase. J Nat Prod 78:335-338.


Shabuer G, Ishida K, Pidot SJ, Roth M, Dahse H-M, Hertweck C (2015) Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory. Science 350 (6261):670-674.


Shelest E, Heimerl N, Fichtner M, Sasso S (2015) Multimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans. BMC Genomics 16:15.


Stöckel S, Stanca AS, Helbig J, Rösch P, Popp J (2015) Raman spectroscopic monitoring of the growth of pigmented and non-pigmented Mycobacteria. Anal Bioanal Chem 407:8919-8923.


Vesty EF, Kessler RW, Wichard T, Coates JC (2015) Regulation of gametogenesis and zoosporogenesis in Ulva linza (Chlorophyta): comparison with Ulva mutabilis and potential for laboratory culture. Front Plant Sci 6:15.


Wichard T (2015) Exploring bacteria-induced growth and morphogenesis in the green macroalga order Ulvales (Chlorophyta). Front Plant Sci 6:86.


Wichard T, Charrier B, Mineur F, Bothwell JH, De Clerck O, Coates JC (2015) The green seaweed Ulva: a model system to study morphogenesis. Front Plant Sci 6:72.