Raman Based Analysis of Natural Products in Complex Biosystems
further information on the project …
Raman based approaches allow the chemical imaging of metabolites in complex communities. Raman microscopy, resonance Raman (micro)spectroscopy, SERS and CARS microscopy will be provided to various A, B and C projects, for example: Raman and CARS spectroscopic imaging of macroalgae surfaces and tumor cells; Raman and CARS imaging of gut microbial communities of insects and their influence on the release of metal salts; Raman spectroscopic monitoring of biofilms, their interaction with antibiotics, of siderophores and their influence on microbial communities.
Information Infrastructure/ Chem- and Bioinformatics
Project area INF will manage the storage, archiving, and standardized analyses of experimental high-throughput data generated within the consortium. It will ensure that the data generated within ChemBioSys will be findable, accessible, interoperable and reproducible (FAIR) both by researchers within the consortium as well as by scientists world-wide, as soon as the consortium has decided to publically release certain datasets. In the light of the challenges in structure elucidation of the identified mediators, integrated solution for the dereplication and de-novo structure elucidation of natural products in complex communities will be additionally pursued.further information on the project …